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ABSTRACT

This research characterized and optimized a GnRH-based spawning induction technology for striped bass and related species, using sustained-release biodegradable GnRHa delivery systems. The recipient demonstrated that D-Arg6 -cGnRHII (an analog of a common perciform GnRH) is equally important compared to the D-Ala6 -mGnRH agonist (which is currently used in culture situations). Doses for acute administration and analog effectiveness in eliciting in vivo gonadotropin release also were established. Finally, the data demonstrated rapid and satisfactory clearance rates of the GnRHa from fish tissues. This research was conducted in view of facilitating regulatory approval of the GnRH-based technology and its large-scale application in the aquaculture industry.